- Title
- Factors influencing diabetes-related foot ulcer healing in Australian adults: A prospective cohort study
- Creator
- Tehan, Peta Ellen; Burrows, Tracy; Hawes, Morgan Brian; Linton, Clare; Norbury, Kate; Peterson, Benjamin; Walsh, Annie; White, Diane; Chuter, Vivienne Helaine
- Relation
- Diabetic Medicine Vol. 40, Issue 1, no. e14951
- Publisher Link
- http://dx.doi.org/10.1111/dme.14951
- Publisher
- Wiley-Blackwell
- Resource Type
- journal article
- Date
- 2023
- Description
- OBJECTIVE: Diabetes-related foot ulceration (DFU) is a common limb-threatening condition, which is complex and subsequently challenging to manage. The aim of this study was to determine the contribution of a range of clinical and social factors to the healing of diabetes-related foot ulceration in an Australian population. RESEARCH DESIGN AND METHODS: This was a prospective cohort study of individuals with diabetes-related foot ulceration (DFU). Age, sex, medical history, medications, dietary supplementation (e.g. vitamin C intake) and smoking history were elicited at baseline. The index of relative socio-economic disadvantage (IRSD) was calculated. The Australian Eating Survey and International Physical Activity Questionnaire-short were administered. Wound history, size, grade, time to healing and infection were captured and monitored over 6 months. Logistic regression was performed to determine the relationship between healing and diet quality, toe systolic pressure, wound size at, IRSD, infection and previous amputation. RESULTS: A total of 117 participants were included. The majority were male n = 96 (82%), socio-economically disadvantaged (mean IRSD 965, SD 60), and obese (BMI 36 kg/m2 , SD 11) with a long history of diabetes (20 years, SD 11). Wounds were predominantly neuropathic (n = 85, 73%) and classified 1A (n = 63, 54%) on the University of Texas wound classification system with few infections (n = 23, 16%). Dietary supplementation was associated with 4.36 increased odds of healing (95% 1.28-14.84, p = 0.02), and greater levels of socio-economic advantage were also associated with increased odds of healing (OR 1.01, 95% CI 1.01-1.02, p = 0.03). CONCLUSIONS: In this cohort study of predominantly neuropathic, non-infected DFU, individuals who had greater levels of socio-economic advantage had significantly greater odds of DFU healing. Diet quality was poor in most participants, with individuals taking supplementation significantly more likely to heal.
- Subject
- cohort; diabetes-related foot ulceration; dietary intake; socio-economic disadvantage; supplementation; ulcer; SDG 3; Sustainable Development Goals
- Identifier
- http://hdl.handle.net/1959.13/1478877
- Identifier
- uon:50246
- Identifier
- ISSN:0742-3071
- Rights
- x
- Language
- eng
- Reviewed
- Hits: 2284
- Visitors: 2284
- Downloads: 0
Collections
Goal 3: Good Health and Well-Being
| Thumbnail | File | Description | Size | Format |
|---|